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Antioxidant Research

 

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Yamakoshi, J., et al. Proanthocyanidin-rich extract from grape seeds attenuates the development of aortic atherosclerosis in cholesterol-fed rabbits. Atherosclerosis 142:139-149, 1999.

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Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated–p53 activation


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Aging and the role of reactive nitrogen species.

 

Flavonoids, a class of natural products of high pharmacological potency.

Red wine polyphenols and inhibition of platelet aggregation: possible mechanisms, and potential use in health promotion and disease prevention.

Free radicals as mediators of tissue injury and disease.

 

Intrinsic dissolution rates of tablet fillers and binders and their influence on the dissolution of drugs from tablet formulations.

 

News Flashes

Pine bark provides hope for cancer patients

A new product which could help reduce the debilitating effects of chemotherapy and radiotherapy among cancer sufferers is being produced from pine bark.

 

A new product which could help reduce the debilitating effects of chemotherapy and radiotherapy among cancer sufferers is being produced from pine bark.

Researchers from HortResearch and Enzo Nutraceuticals in New Zealand are working together to develop a range of botanical drug products which they hope will be effective in fighting not only cancer but also other serious diseases such as Alzheimer's, heart disease and stroke.Aegis BioActives, as the joint venture between the two companies is called, was formed after 15 months of collaborative research led by cell biologist Dr Iona Weir.

 

Weir had been testing compounds for ways to inhibit cell death when she came across Enzo's dietary supplement Enzogenol, which contains antioxidants extracted from pinus radiate bark. She discovered that the extract was more potent than anything else she had tested, and this discovery was the start of the collaboration between the two companies.